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KMID : 1094020080250040245
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Journal of Veterinary Clinics
2008 Volume.25 No. 4 p.245 ~ p.248
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Therapeutic Effect of Oyaksungisan in Dogs with Facial Nerve Paralysis
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Eom Chang-Sub
Jun Hyung-Kyou
Kim Sang-Hun
Yun Hyo-In
Kim Myung-Cheol
Kim Duck-Hwan
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Abstract
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Herbal medicines are widely used to treat a variety of human diseases. However, therapeutic effect of herbal medicine on the canine facial nerve paralysis (FNP) has not been investigated. This study examined therapeutic effects of Oyaksungisan on the canine FNP. Ten dogs with the induced canine FNP were equally divided into the control and an herbal medicine-treated groups (5 dogs, Oyaksungisan-treated group), respectively. No treatment was given to the control group. In the Oyaksungisan-treated group, Oyaksungisan was administered orally, twice per day for 2 weeks (50 mg/kg) after inducing FNP. Significant differences in the clinical scores were detected between the Oyaksungisan-treated and control groups on day 14 (p < 0.05). The serum creatine kinase (CK) activities in the Oyaksungisan-treated group showed a tendency to decrease but there was no significant difference compared with those of the control group. In conclusion, Oyaksungisan was effective for the induced canine FNP.
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KEYWORD
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Oyaksungisan, canine, facial nerve paralysis
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